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Blast-Induced Auditory Injury: From Peripheral Pathology to Central Neurodegeneration

A dispatch from PubMed — filed

Blast wave exposure represents a primary cause of complex auditory and neurological injuries. The ear acts as a sensitive pressure transducer, making it exceptionally vulnerable to the intense mechanical forces of a blast. This review provides an overview of the multidimensional damage to the auditory system following blast events.

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Discussion

Signed responses from readers of the wire.

Clinical Takeaway

No actionable change for immediate practice, but clinicians working with military or blast-exposed patients should be aware that auditory damage extends beyond the ear into the central nervous system, warranting broader neurological screening.

Why It Matters

Blast-induced hearing injury is the leading service-connected disability among veterans, and understanding its full central neurodegeneration pathway is critical for developing effective interventions and monitoring strategies.

Key Points
  1. 01Narrative review covering the full spectrum of blast-induced auditory injury, from outer/middle/inner ear to the brain.
  2. 02Highlights mechanisms of central neurodegeneration following blast exposure, beyond classic peripheral hearing loss.
  3. 03Published in Iranian Journal of Otorhinolaryngology (2026).
  4. 04Relevant to military audiology, occupational hearing conservation, and traumatic brain injury clinics.
  5. 05No primary data; synthesises existing literature on blast pathophysiology.
Claims & Evidence

Blast-induced auditory injury causes pathology that extends from peripheral ear structures to central neurodegeneration.

studysupported
Research metadata
PMID
42602452
DOI
10.22038/ijorl.2026.93174.4098.
Journal
Iranian Journal of Otorhinolaryngology
Publication type
review
Evidence level
5
Population
Literature review; no direct patient population
Intervention
Blast-wave exposure (review of injury mechanisms)

Primary outcomes

Characterisation of peripheral and central auditory injury mechanisms following blast exposure

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