/Objectives: To characterize the clinical and imaging phenotypes of schwannomatosis (SWN) in children, adolescents, and young adults (AYAs).
✦ The floor
Discussion
Signed responses from readers of the wire.
Audiologists seeing young patients with unexplained hearing loss or vestibular symptoms should be aware of schwannomatosis as a differential diagnosis, but this retrospective single-center case series does not change established screening or management protocols.
Characterizing schwannomatosis in pediatric and young-adult populations expands understanding of a rare condition that can present with audiological symptoms and may inform earlier referral pathways.
- 01Single-center retrospective cohort study of schwannomatosis in children, adolescents, and young adults.
- 02Describes clinical and MRI/imaging phenotypes specific to younger age groups.
- 03Schwannomatosis can involve auditory nerve tumors, making it relevant to audiological practice.
- 04Retrospective design and single-center setting limit generalizability of findings.
- 05Findings may support earlier specialist referral when schwannomatosis is suspected in young patients.
Schwannomatosis in children, adolescents, and young adults has distinct clinical and imaging phenotypes compared to adult presentations.
studypartially supported- PMID
- 42650012
- DOI
- 10.3390/cancers18162701.
- Journal
- Cancers
- Publication type
- research_article
- Evidence level
- 4
- Population
- Children, adolescents, and young adults with schwannomatosis at a single center
- Intervention
- Clinical and imaging characterization of schwannomatosis
Primary outcomes
Clinical phenotype description; Imaging phenotype characterization (MRI findings)