Precision Balance Rehabilitation in Progressive Multifocal Leukoencephalopathy: A Novel Case Report

AND PURPOSE: Progressive Multifocal Leukoencephalopathy (PML) is a demyelinating disease of white matter, primarily affecting immunocompromised patients. PML survivors often experience disability marked by ataxia and balance deficits. Rehabilitation research for this population is limited. This case report describes the design, application, and efficacy of a balance rehabilitation program for a patient with PML....

Single case report on a rare condition; no actionable change to standard vestibular rehabilitation practice is warranted based on this evidence alone.

PML-related vestibular dysfunction is poorly documented, and this case adds to the sparse literature on rehabilitating balance deficits in rare neuro-immunological conditions relevant to audiologists and vestibular specialists.

1. 01Describes a 'precision balance rehabilitation' approach for a PML survivor with vestibular/balance deficits.
2. 02PML is rare and predominantly affects immunocompromised individuals (e.g., HIV/AIDS, transplant patients).
3. 03Published as a case report — lowest level of individual study evidence.
4. 04Vestibular rehabilitation in PML survivors is not well-studied, making this a novel clinical description.
5. 05Findings cannot be generalized without larger studies.

PMID

42158464

DOI

10.2147/IMCRJ.S578185.

Journal

International Medical Case Reports Journal

Publication type

case_report

Evidence level

4

Sample size

1

Population

Single adult PML survivor with vestibular and balance deficits

Intervention

Precision balance rehabilitation program