The goal of this study is to evaluate the pooled diagnostic performance of cervical (cVEMP) and ocular (oVEMP) vestibular-evoked myogenic potentials for Acute Unilateral Vestibulopathy. DATA SOURCES: MEDLINE, EMBASE, Scopus, and Cochrane Central were searched for relevant articles from inception to October 2025. REVIEW
✦ The floor
Discussion
Signed responses from readers of the wire.
This meta-analysis provides pooled sensitivity and specificity estimates for cVEMP and oVEMP in acute unilateral vestibulopathy; clinicians should review the specific figures when selecting vestibular diagnostic protocols, though individual lab normative data remain essential.
Establishing the pooled diagnostic accuracy of VEMP testing for acute unilateral vestibulopathy helps standardize vestibular diagnostic pathways and supports evidence-based test selection in balance clinics.
- 01Systematic review and meta-analysis published in Otolaryngology–Head and Neck Surgery.
- 02Evaluates both cVEMP (cervical) and oVEMP (ocular) for diagnosing acute unilateral vestibulopathy.
- 03Pooled diagnostic performance metrics (sensitivity/specificity) are derived from multiple prior studies.
- 04Findings can inform which VEMP modality is more useful for this specific diagnosis.
- 05Quality and heterogeneity of included studies will influence reliability of pooled estimates.
cVEMP and oVEMP have quantifiable pooled diagnostic sensitivity and specificity for acute unilateral vestibulopathy.
studysupported- PMID
- 42788762
- DOI
- 10.1002/ohn.70457.
- Journal
- Otolaryngology–Head and Neck Surgery
- Publication type
- meta_analysis
- Evidence level
- 1a
- Population
- Patients presenting with acute unilateral vestibulopathy evaluated with VEMP testing
- Intervention
- Cervical VEMP (cVEMP) and ocular VEMP (oVEMP) testing
- Comparator
- Clinical or imaging-based diagnosis of acute unilateral vestibulopathy
Primary outcomes
Pooled diagnostic sensitivity of cVEMP and oVEMP; Pooled diagnostic specificity of cVEMP and oVEMP