False-negative transcranial facial motor evoked potential (FMEP) findings have previously been recognized retrospectively through discrepancies between preserved intraoperative FMEPs and postoperative facial palsy. To the best of our knowledge, no previous report has demonstrated a false-negative FMEP finding intraoperatively using direct facial nerve stimulation....
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Discussion
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Surgeons operating on vestibular schwannoma should consider supplementing standard facial motor evoked potential monitoring with direct facial nerve stimulation to detect false-negative signals that could mask impending nerve injury.
False-negative intraoperative neuromonitoring is a known risk in vestibular schwannoma surgery; this case highlights a specific rescue technique that may reduce rates of postoperative facial palsy — a major quality-of-life outcome for patients.
- 01Standard facial motor evoked potentials (fMEPs) produced a false-negative result during vestibular schwannoma resection.
- 02Direct facial nerve stimulation successfully detected the monitoring failure in real time.
- 03Timely detection allowed surgical adjustment, potentially preventing permanent facial nerve damage.
- 04Case underscores limitations of relying on a single intraoperative neuromonitoring modality.
- 05Published in Surgical Neurology International.
Direct facial nerve stimulation can detect false-negative facial motor evoked potentials during vestibular schwannoma surgery.
studypartially supportedFalse-negative facial motor evoked potentials represent a real intraoperative risk during vestibular schwannoma resection.
studysupported- PMID
- 42974267
- DOI
- 10.25259/SNI_941_2026.
- Journal
- Surgical Neurology International
- Publication type
- case_report
- Evidence level
- 4
- Sample size
- 1
- Population
- Single patient undergoing vestibular schwannoma surgical resection with intraoperative neuromonitoring
- Intervention
- Direct facial nerve stimulation as adjunct to standard facial motor evoked potential monitoring
- Comparator
- Standard facial motor evoked potential (fMEP) monitoring alone
Primary outcomes
Detection of false-negative facial motor evoked potential; Facial nerve integrity preservation