Primary Sjögren's syndrome (pSS), a chronic autoimmune disorder primarily affecting the exocrine glands, typically presents with sicca symptoms. Neurological involvement in pSS is uncommon as an initial presentation. Ischemic stroke, in particular, is a rare manifestation, while seizures are more commonly secondary to underlying structural or inflammatory central nervous system involvement....
✦ The floor
Discussion
Signed responses from readers of the wire.
No actionable change for audiology practice; while Sjögren's syndrome can cause inner-ear symptoms, this single case report about stroke as an initial manifestation does not alter audiological screening or management protocols.
Audiologists should be aware that autoimmune conditions like Sjögren's syndrome can present with varied neurological symptoms, as some patients may first present with auditory or vestibular complaints before a formal diagnosis.
- 01Single case report: ischemic stroke (blood-flow-blocking stroke) presented as the first sign of primary Sjögren's syndrome.
- 02Sjögren's syndrome rarely causes neurological symptoms, making this an atypical presentation.
- 03Autoimmune inner-ear disease is a known — though separate — concern in Sjögren's syndrome.
- 04Case reports cannot establish causation or prevalence.
- 05Clinicians should consider autoimmune workup in unexplained neurological or audiovestibular presentations.
Ischemic stroke can be an initial manifestation of primary Sjögren's syndrome.
studypartially supported- PMID
- 42544321
- DOI
- 10.7759/cureus.113812.
- Journal
- Cureus
- Publication type
- case_report
- Evidence level
- 4
- Sample size
- 1
- Population
- Single patient presenting with ischemic stroke as initial manifestation of primary Sjögren's syndrome
Primary outcomes
Description of stroke as initial presentation of Sjögren's syndrome; Neurological outcome