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Vestibular Dysfunction and Postural Changes in Children With Congenital Cytomegalovirus: A Systematic Review

A dispatch from PubMed — filed

The aim of this study was to investigate the prevalence of vestibular and/or postural balance alterations in children with congenital cytomegalovirus (cCMV) and to determine the association between the infection and these impairments compared to a control group.

Clinical Takeaway

Audiologists managing children with congenital CMV should routinely consider vestibular assessment, as this systematic review indicates vestibular dysfunction and postural imbalance are prevalent in this population.

Why It Matters

Vestibular involvement in cCMV is often under-recognized; a systematic review synthesizing prevalence data can prompt broader adoption of vestibular screening protocols in this high-risk pediatric group.

Key Points
  1. 01Systematic review of vestibular dysfunction and postural balance problems in children with congenital CMV infection.
  2. 02Inner-ear (cochlear and vestibular) damage from cCMV may co-occur, making combined audiological-vestibular assessment important.
  3. 03Published in Journal of Speech, Language, and Hearing Research (2026).
  4. 04Findings support adding vestibular evaluation to the standard cCMV follow-up pathway for children.
  5. 05Prevalence estimates synthesized across multiple studies provide stronger evidence than single studies.
Claims & Evidence

Vestibular dysfunction is prevalent in children with congenital CMV infection.

studysupported

Postural balance alterations are associated with congenital CMV infection in children.

studysupported
Research metadata
PMID
42139663
DOI
10.1044/2026_JSLHR-25-00586.
Journal
Journal of Speech, Language, and Hearing Research
Publication type
systematic_review
Evidence level
2a
Population
Children with congenital cytomegalovirus (cCMV) infection
Intervention
Systematic review of vestibular function and postural balance assessments in cCMV-affected children

Primary outcomes

Prevalence of vestibular dysfunction in children with cCMV; Prevalence of postural balance alterations in children with cCMV

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