In foot and ankle surgery, prolonged analgesia after popliteal sciatic nerve block (PSNB) may be accompanied by delayed motor recovery. The effects of sequential lidocaine and liposomal bupivacaine (LB), particularly on early motor function, remain uncertain.
✦ The floor
Discussion
Signed responses from readers of the wire.
No actionable change for audiologists — this RCT concerns regional anesthesia for foot and ankle surgery and has no relevance to audiology clinical practice.
This study has no direct relevance to the audiology field; it was likely indexed alongside audiology content in error or via a broad PubMed feed.
- 01RCT comparing sequential lidocaine + liposomal bupivacaine for popliteal sciatic nerve block.
- 02Primary focus is analgesic duration vs. motor recovery trade-offs in foot/ankle surgery.
- 03No audiology, hearing, or vestibular content is present.
- 04Findings pertain to anesthesiology and orthopedic/podiatric surgery only.
- 05Audiologists and hearing specialists should disregard this article as out of scope.
Sequential lidocaine followed by liposomal bupivacaine prolongs analgesic duration compared to single-agent blocks in popliteal sciatic nerve block.
studyunclear- PMID
- 42964702
- DOI
- 10.2147/DDDT.S647879.
- Journal
- Drug Design, Development and Therapy
- Publication type
- research_article
- Evidence level
- 1b
- Population
- Patients undergoing foot and ankle surgery receiving popliteal sciatic nerve block
- Intervention
- Sequential lidocaine followed by liposomal bupivacaine for popliteal sciatic nerve block
- Comparator
- Single-agent nerve block (comparator details not specified in abstract)
Primary outcomes
Duration of analgesia; Time to motor recovery