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Opioid-Induced Nausea and Vomiting in Patients With Cancer: A Narrative Review

A dispatch from PubMed — filed

Opioid-induced nausea and vomiting (OINV) represent a frequent and clinically significant complication in patients with cancer. They negatively affect adherence to analgesic therapy, pain control, and overall quality of life. Their pathophysiology is multifactorial and involves activation of the chemoreceptor trigger zone through dopaminergic and serotonergic pathways, impairment of gastrointestinal motility leading...

Clinical Takeaway

No actionable change for audiology practice; this article addresses opioid-induced nausea and vomiting in oncology and has no meaningful clinical relevance to hearing health.

Why It Matters

This article has minimal relevance to the audiology field; it appears in this feed likely due to indexing overlap and can be deprioritised by audiology readers.

Key Points
  1. 01Narrative review published in Cureus on opioid-induced nausea and vomiting (OINV) in cancer patients.
  2. 02Focuses on how OINV reduces analgesic (pain medicine) adherence in oncology settings.
  3. 03No direct audiology, hearing loss, or vestibular content identified.
  4. 04Opioids have known ototoxic (hearing-damaging) potential, but this review does not address that angle.
  5. 05Audiologists involved in ototoxicity monitoring programmes may note tangential relevance only.
Research metadata
PMID
42291947
DOI
10.7759/cureus.108798.
Journal
Cureus
Publication type
review
Evidence level
5
Population
Cancer patients receiving opioid analgesics
Intervention
Opioid analgesics

Primary outcomes

Incidence and management of opioid-induced nausea and vomiting; Impact on analgesic adherence

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