To prospectively evaluate audiovestibular outcomes following parathyroidectomy in patients with primary hyperparathyroidism (pHPT) using a comprehensive battery of audiological, vestibular, and patient-reported outcome measures.
✦ The floor
Discussion
Signed responses from readers of the wire.
If surgery to correct overactive parathyroid glands is shown to improve hearing and balance outcomes, audiologists should consider screening for primary hyperparathyroidism in patients with unexplained audiovestibular symptoms; however, the prospective design without a control arm limits causal conclusions.
Primary hyperparathyroidism is an underrecognized potential contributor to audiovestibular dysfunction, and evidence that parathyroidectomy improves these outcomes could open a new referral pathway between audiology and endocrine surgery.
- 01Prospective study measuring hearing and balance outcomes before and after parathyroid surgery.
- 02Patients had primary hyperparathyroidism — a condition where overactive glands raise blood calcium levels.
- 03Elevated calcium may negatively affect the inner ear's hearing and balance systems.
- 04Correcting the calcium imbalance via surgery may reverse some audiovestibular deficits.
- 05No control group was described, limiting causal interpretation of results.
Parathyroidectomy improves audiovestibular outcomes in patients with primary hyperparathyroidism.
studypartially supportedPrimary hyperparathyroidism negatively affects hearing and vestibular function.
studypartially supported- PMID
- 42568741
- DOI
- 10.1002/lio2.70533.
- Journal
- Laryngoscope Investigative Otolaryngology
- Publication type
- research_article
- Evidence level
- 2b
- Population
- Patients with primary hyperparathyroidism undergoing parathyroidectomy
- Intervention
- Parathyroidectomy
Primary outcomes
Audiological outcomes post-parathyroidectomy; Vestibular outcomes post-parathyroidectomy