Long-Term Outcomes of Subtotal Resection for Large Vestibular Schwannomas: Results From the Acoustic Neuroma Subtotal Resection Study-Part II- Tumor Regrowth

AND OBJECTIVES: Subtotal resection (STR) of large vestibular schwannomas (VS) may achieve better facial nerve outcomes. However, this approach, involving less-than-total tumor removal, may also increase the risk of regrowth. The objective was to examine differences in the regrowth rate based on the extent of resection in patients with large VS.

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For audiologists managing patients post-vestibular schwannoma surgery, this study reinforces awareness that subtotal resection carries measurable regrowth risk requiring long-term radiologic surveillance; refer patients accordingly and coordinate with neurosurgery/neuro-oncology teams for monitoring protocols.

As subtotal resection becomes an increasingly accepted strategy for large vestibular schwannomas, long-term regrowth data are critical for setting realistic patient expectations and designing post-operative surveillance pathways.

1. 01Part II of a multi-part study specifically tracks long-term tumor regrowth after intentional subtotal resection of large vestibular schwannomas.
2. 02Published in Neurosurgery (PMID 42714141), providing peer-reviewed longitudinal evidence.
3. 03Regrowth rates and time-to-retreatment are key outcomes informing surgical decision-making.
4. 04Findings have direct implications for the multidisciplinary team managing these patients, including audiologists.
5. 05Results complement Parts I and III addressing facial nerve outcomes and perioperative complications respectively.

PMID

42714141

DOI

10.1227/neu.0000000000004200.

Journal

Neurosurgery

Publication type

research_article

Evidence level

2b

Population

Patients undergoing subtotal resection for large vestibular schwannomas

Intervention

Subtotal resection of large vestibular schwannomas