Parkinson's disease (PD) is characterized by progressive motor impairment and large-scale network dysfunction that extends beyond dopaminergic degeneration. Although rehabilitative exercise improves clinical outcomes, its capacity to induce structural brain plasticity remains incompletely understood....
✦ The floor
Discussion
Signed responses from readers of the wire.
No actionable change for audiology practice; this review concerns motor rehabilitation in Parkinson's disease and has no direct clinical implication for hearing or vestibular management.
Parkinson's disease is associated with central auditory processing changes and balance disorders, so understanding exercise-driven neuroplasticity may eventually inform vestibular rehabilitation strategies.
- 01Review summarises how exercise promotes neural network plasticity in Parkinson's disease.
- 02Focuses on motor impairment and large-scale brain network dysfunction.
- 03Exercise-driven neuroplasticity may offer a non-pharmacological treatment pathway.
- 04No direct audiology or hearing-specific findings reported.
- 05Published in Frontiers in Rehabilitation Sciences (DOI: 10.3389/fresc.2026.1859762).
Exercise-driven modulation positively affects neural network plasticity in Parkinson's disease.
studypartially supported- PMID
- 42499958
- DOI
- 10.3389/fresc.2026.1859762.
- Journal
- Frontiers in Rehabilitation Sciences
- Publication type
- review
- Evidence level
- 5
- Population
- People with Parkinson's disease
- Intervention
- Exercise-driven modulation of neural networks
Primary outcomes
Neural network plasticity changes; Motor impairment outcomes