Objectives: The aim of this study was to evaluate long-term changes in transtympanic electrocochleography (TT-ECochG) following vestibular neurectomy in patients with Ménière's disease (MD) and to investigate their relationship with endolymphatic hydrops (EH) degree and hearing outcomes.
✦ The floor
Discussion
Signed responses from readers of the wire.
Preliminary pilot data suggest TT-ECochG changes may track endolymphatic hydrops on MRI after vestibular neurectomy, but the small sample and pilot design mean no practice change is justified yet.
If confirmed in larger studies, correlating non-invasive electrophysiological testing with MRI-detected hydrops could reduce the need for advanced imaging in Ménière's disease monitoring.
- 01Pilot study design with a small Ménière's disease patient cohort post-vestibular neurectomy.
- 02TT-ECochG changes were compared to endolymphatic hydrops severity on MRI longitudinally.
- 03Study investigated whether electrophysiology can serve as a surrogate marker for MRI findings.
- 04Longitudinal design strengthens internal validity but small size limits generalizability.
- 05Results are exploratory; replication in larger cohorts is required.
Changes in TT-ECochG reflect the dynamics of endolymphatic hydrops as seen on MRI in Ménière's disease patients after vestibular neurectomy.
studypartially supported- PMID
- 42795936
- DOI
- 10.3390/jcm15187164.
- Journal
- Journal of Clinical Medicine
- Publication type
- research_article
- Evidence level
- 4
- Population
- Patients with severe Ménière's disease who underwent vestibular neurectomy
- Intervention
- Transtympanic electrocochleography (TT-ECochG) monitoring post-vestibular neurectomy
- Comparator
- MRI assessment of endolymphatic hydrops
Primary outcomes
Longitudinal TT-ECochG parameter changes; Correlation of TT-ECochG with endolymphatic hydrops on MRI