Despite the fact that acute persistent vertigo can be a presenting sign of stroke, early bedside risk assessment continues to be particularly difficult. In order to predict clinically detected strokes among patients who were experiencing acute persistent vertigo, our objective was to create and internally validate a multivariable model....
This internally validated stroke-risk prediction model for acute persistent vertigo is not yet ready for clinical use — audiologists and emergency clinicians should await external validation before applying it to triage decisions.
A validated stroke-risk stratification tool for acute persistent vertigo could improve emergency triage accuracy and reduce missed strokes, which is a known and serious diagnostic challenge at the interface of neurology and vestibular medicine.
- 01Multivariable prediction model developed to distinguish stroke from vestibular causes of acute persistent vertigo.
- 02Model was only internally validated — external validation in independent populations is needed.
- 03Published in Frontiers in Neurology; cross-sectional or retrospective design implied by methodology.
- 04Stroke is a known but underdiagnosed cause of acute vertigo in emergency settings.
- 05Relevant for audiologists and vestibular specialists involved in triage or co-management.
A multivariable prediction model can stratify stroke risk in patients presenting with acute persistent vertigo.
studypartially supported- PMID
- 42422204
- DOI
- 10.3389/fneur.2026.1822762.
- Journal
- Frontiers in Neurology
- Publication type
- research_article
- Evidence level
- 4
- Population
- Patients presenting with acute persistent vertigo evaluated for stroke risk
- Intervention
- Development and internal validation of a multivariable stroke-risk prediction model
Primary outcomes
Discrimination of stroke vs. non-stroke etiology in acute persistent vertigo; Internal validation performance metrics of the prediction model