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Multisensory dysfunction across sleep disorders: A systematic review of 31 human modalities

A dispatch from PubMed — filed

Sleep disorders are increasingly understood as systems-level conditions in which the brain and body reweight sensory evidence from the external world and internal milieu. We systematically reviewed human evidence for sensory and multisensory dysfunction across sleep disorders and experimental sleep loss....

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Discussion

Signed responses from readers of the wire.

Clinical Takeaway

No actionable change for audiology practice at this time; findings are preliminary and primarily relevant to researchers studying sensory processing in sleep disorders.

Why It Matters

Understanding how sleep disorders systematically disrupt multisensory processing — including auditory and vestibular function — may reshape how audiologists screen and counsel patients with co-occurring sleep and hearing complaints.

Key Points
  1. 01Systematic review covered 31 human sensory modalities across multiple sleep disorder categories.
  2. 02Sleep disruption alters how the brain 'reweights' sensory evidence, not just a single modality.
  3. 03Auditory and vestibular systems are likely among the affected modalities.
  4. 04Findings position sleep disorders as systems-level sensory conditions, not isolated deficits.
  5. 05Results may inform future interdisciplinary protocols linking sleep medicine and audiology.
Claims & Evidence

Sleep disorders cause the brain to reweight sensory evidence across at least 31 human sensory modalities.

studypartially supported
Research metadata
PMID
42664585
DOI
10.1016/j.smrv.2026.102363.
Journal
Sleep Medicine Reviews
Publication type
systematic_review
Evidence level
1a
Population
Human participants across studies of various sleep disorders
Intervention
Systematic analysis of sensory modality function across sleep disorder populations

Primary outcomes

Characterisation of multisensory dysfunction across 31 sensory modalities in sleep disorders; Assessment of brain sensory reweighting patterns under disrupted sleep

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