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Clinical outcomes of percutaneous versus peroral intraoperative neuromonitoring strategies in transoral endoscopic thyroidectomy vestibular approach: A retrospective analysis of 2,201 patients

A dispatch from PubMed — filed

Recurrent laryngeal nerve palsy remains a critical complication in transoral endoscopic thyroidectomy vestibular approach. While intraoperative neuromonitoring is employed, the optimal strategy for reducing vocal cord palsy remains a topic of debate.

Clinical Takeaway

No actionable change for audiologists — this is a surgical neuromonitoring study with no direct clinical implications for audiology or hearing care practice.

Why It Matters

For ENT surgeons performing transoral thyroidectomy, the choice of neuromonitoring approach may influence recurrent laryngeal nerve palsy rates, but this finding sits outside the core audiology scope.

Key Points
  1. 01Retrospective analysis of 2,201 patients undergoing transoral endoscopic thyroidectomy vestibular approach (TOETVA).
  2. 02Compared percutaneous vs. peroral intraoperative neuromonitoring (IONM) of the recurrent laryngeal nerve.
  3. 03Primary outcome was recurrent laryngeal nerve palsy (voice-box nerve damage) post-surgery.
  4. 04Published in the journal Surgery (2026).
  5. 05Findings are relevant to surgical ENT teams, not audiologists or hearing specialists.
Claims & Evidence

Percutaneous and peroral intraoperative neuromonitoring strategies differ in clinical outcomes for recurrent laryngeal nerve palsy during TOETVA.

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Research metadata
PMID
42475946
DOI
10.1016/j.surg.2026.110432.
Journal
Surgery
Publication type
research_article
Evidence level
4
Sample size
2,201
Population
Patients undergoing transoral endoscopic thyroidectomy vestibular approach (TOETVA)
Intervention
Peroral intraoperative neuromonitoring of the recurrent laryngeal nerve
Comparator
Percutaneous intraoperative neuromonitoring of the recurrent laryngeal nerve

Primary outcomes

Recurrent laryngeal nerve palsy rate

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