Isolated intracranial metastasis to cerebellopontine angle (CPA) is very rare, as CPA tumors are mostly vestibular schwannomas. CASE DESCRIPTION: We present here a rare case of isolated brain metastasis in CPA primarily arising from gallbladder. A female patient presented with chief complaints of dizziness, difficulty walking, and nausea....
✦ The floor
Discussion
Signed responses from readers of the wire.
This single case report is too preliminary to change clinical practice, but it reinforces that not all CPA masses are vestibular schwannomas — thorough workup including cancer history review is warranted before assuming a benign diagnosis.
Metastatic lesions in the CPA are extremely rare and can mimic vestibular schwannomas on imaging, underscoring the need for differential diagnosis vigilance in this region.
- 01Gallbladder adenocarcinoma presenting as an isolated CPA metastasis is exceptionally rare.
- 02CPA lesions are overwhelmingly vestibular schwannomas; metastases must be considered in atypical cases.
- 03Case reports like this expand the known differential diagnosis for CPA masses.
- 04Clinical history of systemic malignancy should always inform CPA lesion workup.
- 05Published in Surgical Neurology International (SNI); PMID 42974281.
Solitary CPA metastasis from gallbladder adenocarcinoma is a rare clinical entity.
quotepartially supported- PMID
- 42974281
- DOI
- 10.25259/SNI_240_2026.
- Journal
- Surgical Neurology International
- Publication type
- case_report
- Evidence level
- 4
- Sample size
- 1
- Population
- Single patient with gallbladder adenocarcinoma and isolated CPA metastasis
- Intervention
- Diagnosis and clinical characterisation of CPA metastasis from gallbladder adenocarcinoma
Primary outcomes
Clinical and radiological characterisation of the metastatic CPA lesion